ELISA Substrates and Reagents
ABclonal Technology p-RPS6-S235/236
Ribosomes the organelles that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit The protein belongs to the S6E family of ribosomal proteins It is the major substrate of protein kinases in the ribosome with subsets of five C-terminal serine residues phosphorylated by different protein kinases Phosphorylation is induced by a wide range of stimuli including growth factors tumor-promoting agents and mitogens Dephosphorylation occurs at growth arrest The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA As is typical for genes encoding ribosomal proteins there are multiple processed pseudogenes of this gene dispersed through the genome
ABclonal Technology CCL1 Rabbit pAb
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
Medchemexpress LLC Phospho-AKT(S473) antibody (YA5759) | 56 kDa | 50 UL
Phospho-AKT(S473) antibody (YA5759) is a mouse-derived, non-conjugated monoclonal antibody targeting Phospho-AKT(S473). The AKT protein, a member of the AKT kinase family, is pivotal in regulating cellular processes including metabolism, proliferation, survival, growth, and angiogenesis. It functions by phosphorylating numerous downstream substrates, with AKT1 involved in modulating over 100 candidates, orchestrating glucose uptake and storage, protein synthesis, and lipid metabolism. This antibody is a key tool for research into these complex cellular pathways.
- Formulation: supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Purity: affinity chromatography.
- Storage and stability: stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
- Appearance: liquid.
- Applications: WB (1:1000-2000), IHC-P (1:100-200), ICC/IF (1:50-200).
- Shipping: shipped with blue ice.
Medchemexpress LLC Phospho-AKT(S473) Antibody (YA5759) | 56 kDa | 10 UL
Phospho-AKT(S473) Antibody (YA5759) is a mouse-derived, non-conjugated monoclonal antibody specifically designed to target Phospho-AKT(S473). This antibody is supplied in a liquid formulation containing PBS, 50% glycerol, 0.5% BSA, and 0.02% sodium azide. It is purified through affinity chromatography, ensuring high specificity for research applications.
- For research use only
- Monoclonal antibody, mouse-derived
- Targets Phospho-AKT(S473)
- Supplied in PBS with 50% glycerol, 0.5% BSA, 0.02% sodium azide
- Appearance: liquid
- Storage at -20°C for up to 1 year
- Avoid repeated freeze/thaw cycles
- Shipped with blue ice
Sino Biological Recombinant Human BAFF/BLyS/TNFSF13B Protein (Trimer, His Tag), MALS-verified 1 mg
A DNA sequence encoding the Human TNFSF13B (NP_006564.1) (Glu140-Leu285) was expressed with a polyhistidine tag at the N-terminus. This construct has a trimer design.
ABclonal Technology Phospho-SHP2-Y542 Rabbit pAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.